PubMed Journals: J Med Virol
Source: PMID: 32056249
⇦ ⇨ J Med Virol. 2020 Feb 13. doi:
⇩ 10.1002/jmv.25709. [Epub ahead of print]
Overlapping and discrete aspects of the
pathology and pathogenesis of the emerging
human pathogenic coronaviruses SARS-CoV,
MERS-CoV, and 2019-nCoV.
Liu J(1)(2), Zheng X(1)(2), Tong Q(1), Li W(1),
Wang B(1)(2), Sutter K(3)(2), Trilling M(3)(2), Lu
M(3)(2), Dittmer U(3)(2), Yang D(1)(2).
(1) Department of Infectious Diseases, Union
Hospital, Tongji Medical College,
Huazhong University of Science and Technology,
Wuhan, Hubei, China.
(2) Joint International Laboratory of Infection
and Immunity, Huazhong University of Science
and Technology, Wuhan, Hubei, China.
(3) Institute for Virology, University Hospital of
Essen, University of Duisburg-Essen, Essen,
First reported from Wuhan, The People's
Republic of China, on 31 December 2019, the
ongoing outbreak of a novel coronavirus
(2019-nCoV) causes great global concerns.
Based on the advice of the International Health
Regulations Emergency Committee and the
fact that to date 24 other countries also
reported cases, the WHO Director-General
declared that the outbreak of 2019-nCoV
constitutes a Public Health Emergency of
International Concern on 30 January 2020.
Together with the other two highly pathogenic
severe acute respiratory syndrome coronavirus
Middle East respiratory syndrome coronavirus
(MERS-CoV), 2019-nCov and other yet to be
identified coronaviruses pose a global threat to
public health. In this mini-review, we provide a
brief introduction to the pathology and
pathogenesis of SARS-CoV and MERS-CoV
and extrapolate this knowledge to the newly
©2020 Wiley Periodicals, Inc.
DOI: 10.1002/jmv.25709 PMID: 32056249