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			PubMed Journals: Viruses

  Source:		PMID: 32050635


    		Viruses. 2020 Feb 10;12(2). pii: E194. doi:
     		10.3390/v12020194.

			Potential Maternal and Infant Outcomes from
			(Wuhan) Coronavirus 2019-nCoV Infecting
			Pregnant Women: Lessons from SARS, MERS,
			and Other Human Coronavirus Infections.

			Schwartz DA(1), Graham AL(2).

			Author Information
			(1) Medical College of Georgia,
			Augusta University, Augusta, GA 30912, USA.
			(2) Department of Anthropology,
			University of Connecticut, Storrs, CT 06269,
			USA.

			In early December 2019 a cluster of cases of
			pneumonia of unknown cause was identified in
			Wuhan, a city of 11 million persons in the
			People's Republic of China. Further
			investigation revealed these cases to result
			from infection with a newly identified
			coronavirus, termed the 2019-nCoV. The
			infection moved rapidly through China, spread
			to Thailand and Japan, extended into adjacent
			countries through infected persons travelling by
			air, eventually reaching multiple countries and
			continents. Similar to such other coronaviruses
			as those causing the
			Middle East respiratory syndrome (MERS) and
			severe acute respiratory syndrome (SARS), the
			new coronavirus was reported to spread via
			natural aerosols from human-to-human. In the
			early stages of this epidemic the case fatality
			rate is estimated to be approximately 2%, with
			the majority of deaths occurring in special
			populations. Unfortunately, there is limited
			experience with coronavirus infections during
			pregnancy, and it now appears certain that
			pregnant women have become infected during
			the present 2019-nCoV epidemic. In order to
			assess the potential of the Wuhan 2019-nCoV
			to cause maternal, fetal and neonatal morbidity
			and other poor obstetrical outcomes, this
			communication reviews the published data
			addressing the epidemiological and clinical
			effects of SARS, MERS, and other coronavirus
			infections on pregnant women and their infants.
			Recommendations are also made for the
			consideration of pregnant women in the design,
			clinical trials, and implementation of future
			2019-nCoV vaccines.

			DOI: 10.3390/v12020194 PMID: 32050635

			Conflict of interest statement: The authors
			declare no conflict of interest.

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