PubMed Journals: J Hosp Infect

  Source:		PMID: 32035997

    		J Hosp Infect. 2020 Feb 6. pii:
     		S0195-6701(20)30046-3. doi:
			10.1016/j.jhin.2020.01.022. [Epub ahead of

			Persistence of coronaviruses on inanimate
			surfaces and their inactivation with biocidal

			Kampf G(1), Todt D(2), Pfaender S(2),
			Steinmann E(2).

			Author Information
			(1) University Medicine Greifswald, Institute for
			Hygiene and Environmental Medicine,
			Ferdinand-Sauerbruch-Straße, 17475
			Greifswald, Germany. Electronic address:
			(2) Department of Molecular and Medical
			Virology, Ruhr University Bochum,
			Universitätsstrasse 50, 44801 Bochum,

			Currently, the emergence of a novel human
			coronavirus, SARS-CoV-2, has become a
			global health concern causing severe
			respiratory tract infections in humans.
			Human-to-human transmissions have been
			described with incubation times between 2-10
			days, facilitating its spread via droplets,
			contaminated hands or surfaces. We therefore
			reviewed the literature on all available
			information about the persistence of human
			and veterinary coronaviruses on inanimate
			surfaces as well as inactivation strategies with
			biocidal agents used for chemical disinfection,
			e.g. in healthcare facilities. The analysis of 22
			studies reveals that human coronaviruses such
			as Severe Acute Respiratory Syndrome (SARS)
			coronavirus, Middle East Respiratory Syndrome
			(MERS) coronavirus or endemic human
			coronaviruses (HCoV) can persist on inanimate
			surfaces like metal, glass or plastic for up to 9
			days, but can be efficiently inactivated by
			surface disinfection procedures with 62-71%
			ethanol, 0.5% hydrogen peroxide or 0.1%
			sodium hypochlorite within 1 minute. Other
			biocidal agents such as 0.05-0.2%
			benzalkonium chloride or 0.02% chlorhexidine
			digluconate are less effective. As no specific
			therapies are available for SARS-CoV-2, early
			containment and prevention of further spread
			will be crucial to stop the ongoing outbreak and
			to control this novel infectious thread.

			Copyright © 2020 The Healthcare Infection
			Society. Published by Elsevier Ltd. All rights

			DOI: 10.1016/j.jhin.2020.01.022
			PMID: 32035997

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