*nlm.life
			PubMed Journals: Cell Host Microbe

  Source:		PMID: 32035028


    		Cell Host Microbe. 2020 Feb 7. pii:
     		S1931-3128(20)30072-X. doi:
			10.1016/j.chom.2020.02.001. [Epub ahead of
			print]

			Genome Composition and Divergence of the
			Novel Coronavirus (2019-nCoV) Originating in
			China.

			Wu A(1), Peng Y(2), Huang B(3), Ding X(1),
			Wang X(1), Niu P(3), Meng J(1), Zhu Z(2), Zhang
			Z(2), Wang J(1), Sheng J(1), Quan L(4), Xia Z(5),
			Tan W(6), Cheng G(7), Jiang T(8).

			Author Information
			(1) Center for Systems Medicine, Institute of
			Basic Medical Sciences,
			Chinese Academy of Medical Sciences &
			Peking Union Medical College, Beijing 100005,
			China; Suzhou Institute of Systems Medicine,
			Suzhou, Jiangsu 215123, China.
			(2) College of Biology, Hunan Provincial Key
			Laboratory of Medical Virology, Hunan
			University, Changsha 410082, China.
			(3) Key Laboratory of Medical Virology, National
			Health and Family Planning Commission,
			National Institute for Viral Disease Control and
			Prevention, China CDC, Beijing 102206, China.
			(4) School of Computer Science and
			Technology, Soochow University, Suzhou,
			China.
			(5) Department of Cell Biology, School of Life
			Science, Central South University, Changsha
			410013, China; Hunan Key Laboratory of
			Animal Models for Human Diseases, Hunan Key
			Laboratory of Medical Genetics & Center for
			Medical Genetics, School of Life Science,
			Central South University, Changsha 410013,
			China.
			(6) Key Laboratory of Medical Virology, National
			Health and Family Planning Commission,
			National Institute for Viral Disease Control and
			Prevention, China CDC, Beijing 102206, China.
			Electronic address: tanwj@ivdc.chinacdc.cn.
			(7) Department of Microbiology, Immunology
			and Molecular Genetics,
			University of California, Los Angeles, Los
			Angeles, USA. Electronic address:
			gcheng@mednet.ucla.edu.
			(8) Center for Systems Medicine, Institute of
			Basic Medical Sciences, Chinese Academy of
			Medical Sciences & Peking Union Medical
			College, Beijing 100005, China; Suzhou
			Institute of Systems Medicine, Suzhou, Jiangsu
			215123, China. Electronic address:
			taijiao@ibms.pumc.edu.cn.

			An in-depth annotation of the newly discovered
			coronavirus (2019-nCoV) genome has revealed
			differences between 2019-nCoV and
			severe acute respiratory syndrome (SARS) or
			SARS-like coronaviruses. A systematic
			comparison identified 380 amino acid
			substitutions between these coronaviruses,
			which may have caused functional and
			pathogenic divergence of 2019-nCoV.

			Copyright © 2020. Published by Elsevier Inc.

			DOI: 10.1016/j.chom.2020.02.001
			PMID: 32035028

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