PubMed Journals: Science
Source: PMID: 12730500
⇦ ⇨ Science. 2003 May 30;300(5624):1394-9. Epub
⇩ 2003 May 1.
Characterization of a novel coronavirus
associated with severe acute respiratory syndrome.
Rota PA(1), Oberste MS, Monroe SS, Nix WA,
Campagnoli R, Icenogle JP, Peñaranda S,
Bankamp B, Maher K, Chen MH, Tong S, Tamin
A, Lowe L, Frace M, DeRisi JL, Chen Q, Wang
D, Erdman DD, Peret TC, Burns C, Ksiazek
TG, Rollin PE, Sanchez A, Liffick S, Holloway
B, Limor J, McCaustland K, Olsen-Rasmussen
M, Fouchier R, Günther S, Osterhaus AD,
Drosten C, Pallansch MA, Anderson LJ, Bellini
(1) National Center for Infectious Diseases,
Centers for Disease Control and Prevention,
Atlanta, GA 30333, USA. email@example.com
Comment in Science. 2003 May 30;300(5624):1377-8.
In March 2003, a novel coronavirus (SARS-CoV)
was discovered in association with cases
of severe acute respiratory syndrome (SARS).
The sequence of the complete genome of SARS-CoV
was determined, and the initial characterization
of the viral genome is presented in this
report. The genome of SARS-CoV is 29,727
nucleotides in length and has 11 open reading
frames, and its genome organization is similar
to that of other coronaviruses. Phylogenetic
analyses and sequence comparisons showed
that SARS-CoV is not closely related to
any of the previously characterized coronaviruses.
DOI: 10.1126/science.1085952 PMID: 12730500
[Indexed for MEDLINE]