PubMed Journals: Science

  Source:		PMID: 11951031
  Download:	https://science.sciencemag.org/content/296/5566/298/tab-pdf

    		Science. 2002 Apr 12;296(5566):298-300.
			Decoding the patterns of self and nonself
			by the innate immune system.

			Medzhitov R(1), Janeway CA Jr.

			Author Information
			(1) Howard Hughes Medical Institute and
			Section of Immunobiology, Yale University
			School of Medicine, New Haven, CT 06520,
			USA. ruslan.medzhitov@yale.edu

			The innate immune system evolved several
			strategies of self/nonself discrimination
			that are based on the recognition of molecular
			patterns demarcating infectious nonself,
			as well as normal and abnormal self. These
			patterns are deciphered by receptors that
			either induce or inhibit an immune response,
			depending on the meaning of these signals.

			DOI: 10.1126/science.1068883 PMID: 11951031
			[Indexed for MEDLINE]

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